Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736844 | 0.79 | CA12 (0.46) | CYP3A4GAAALDH1A1CA1CA2 | |
| SCHEMBL121510 | 0.78 | GAA (0.36) | CYP3A4NQO2GAAALDH1A1MAPK1 | |
| SCHEMBL144288 | 0.74 | GAA (0.53) | NQO2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL1817672 | 0.73 | CA1 (0.51) | CYP3A4GAAALDH1A1MAPK1CA1 | |
| SCHEMBL14565684 | 0.72 | CA1 (0.39) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL31515128 | 0.72 | NQO2 (0.46) | CYP3A4NQO2GAAALDH1A1CA1 | |
| SCHEMBL31515141 | 0.72 | CA12 (0.46) | CYP3A4GAAALDH1A1CA1CA2 | |
| SCHEMBL31515130 | 0.72 | NQO2 (0.46) | CYP3A4NQO2GAAALDH1A1CA1 | |
| SCHEMBL18748546 | 0.71 | KDR (0.34) | CYP3A4ALDH1A1KDM4EMAPTCFTR | |
| SCHEMBL12236619 | 0.70 | CYP3A4 (0.45) | CYP3A4GAAALDH1A1HIF1ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066833-A1 | Methods to synthesize indoles as precursors for pharmaceuticals | SCIOS, INC. (US) | 2007-03-22 | — | — | US | disclosed |
| US-20070066833-A1 | Methods to synthesize indoles as precursors for pharmaceuticals | SCIOS, INC. (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066833-A1 | Methods to synthesize indoles as precursors for pharmaceuticals | IDO1, IDO2, INMT | CYP3A4 26/4885NQO2 681/4885GAA 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.