Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31515141 | 0.92 | CA12 (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5550646 | 0.84 | CYP3A4 (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3131937 | 0.83 | CYP3A4 (0.52) | CA12CA1CA2CA3CA4 | |
| SCHEMBL121510 | 0.82 | GAA (0.36) | CA1CA2CA9CYP3A4ALDH1A1 | |
| SCHEMBL31086529 | 0.81 | KDM4E (0.43) | CYP3A4ALDH1A1TP53CASP1KDM4E | |
| SCHEMBL16539867 | 0.81 | GAA (0.55) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2854043 | 0.81 | CA1 (0.50) | CA12CA1CA2CA3CA4 | |
| SCHEMBL14565682 | 0.79 | CYP3A4 (0.34) | CA1CA2CA9CYP3A4ALDH1A1 | |
| SCHEMBL6437742 | 0.79 | CA1 (0.53) | CA12CA1CA2CA3CA4 | |
| SCHEMBL144288 | 0.78 | GAA (0.53) | ALDH1A1TSHRCASP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854087-B | Indole carboxamide derivatives as P2X receptor antagonists | 埃科特莱茵药品有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104854087-A | As P2X7Indole carboxamide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2015-08-19 | — | — | CN | disclosed |
| WO-2013167633-A1 | ACRYLAMIDE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-11-14 | — | — | WO | disclosed |
| WO-2008079105-A1 | METHODS TO SYNTHESIZE INDOLES AS PRECURSORS FOR PHARMACEUTICALS | SCIOS INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008079105-A1 | METHODS TO SYNTHESIZE INDOLES AS PRECURSORS FOR PHARMACEUTICALS | SCIOS INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20070066833-A1 | Methods to synthesize indoles as precursors for pharmaceuticals | SCIOS, INC. (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066833-A1 | Methods to synthesize indoles as precursors for pharmaceuticals | IDO1, IDO2, INMT | CA12 2550/4885CA1 2887/4885CA2 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.