Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284946 | 1.00 | PGR (0.66) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14568580 | 0.93 | NR3C1 (0.69) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14933691 | 0.93 | NR3C1 (0.69) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14285009 | 0.89 | NR3C1 (0.67) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14284952 | 0.89 | NR3C1 (0.67) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14450055 | 0.88 | NR3C1 (0.70) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14508986 | 0.88 | NR3C1 (0.70) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14565704 | 0.88 | NR3C1 (0.70) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14567812 | 0.88 | NR3C1 (0.70) | PGRNR3C1ARNR3C2LMNA | |
| SCHEMBL14084961 | 0.88 | NR3C1 (0.70) | PGRNR3C1ARNR3C2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196208-B2 | Processes for preparing 7-carboxy substituted steroids | PHARMACIA & UPJOHN COMPANY | 2007-03-27 | — | — | US | disclosed |
| US-20070066579-A1 | 5-androsten-3beta-ol steroid intermediates and processs for their preparation | WHITE MICHAEL J | 2007-03-22 | — | — | US | disclosed |
| US-20070066579-A1 | 5-androsten-3beta-ol steroid intermediates and processs for their preparation | WHITE MICHAEL J | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066579-A1 | 5-androsten-3beta-ol steroid intermediates and processs for their preparation | CYP17A1, NR5A1, HSD3B2 | PGR 102/4885NR3C1 65/4885AR 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.