Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565719 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL14565724 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL14565725 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL14580775 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL14580757 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL291020 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL14565723 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL20930061 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL22460370 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 | |
| SCHEMBL4884297 | 1.00 | TRPM8 (0.68) | TRPM8EPHX1EPHX2MAPTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189760-B2 | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine | MILLENNIUM SPECIALTY CHEMICALS (US) | 2007-03-13 | — | — | US | disclosed |