SCHEMBL291020

SCHEMBL291020

CCOC(=O)CNC(=O)C1CC(C)CCC1C(C)C

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 6/20 0.68
EPHX1 P07099 3/20 0.49
EPHX2 P34913 2/20 0.40
MAPT P10636 1/20 0.39
TRPA1 O75762 2/20 0.37
GAA P10253 1/20 0.37
POLB P06746 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14565719 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14565724 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14565720 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14565725 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14580775 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14580757 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL14565723 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL20930061 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL22460370 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1
SCHEMBL4884297 1.00 TRPM8 (0.68) TRPM8EPHX1EPHX2MAPTTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028893-A Composition and method for producing the same 奇华顿股份有限公司 2026-05-12 CN claimed
EP-4691492-A2 LIQUID COMPOSITIONS Kenvue Brands LLC (US) 2026-02-11 EP claimed
EP-4687503-A1 FUNCTIONALIZED FLEECE MATERIAL PRODUCTION Nicoventures Trading Limited (GB) 2026-02-11 EP claimed
EP-3908266-B1 LIQUID COMPOSITIONS KENVUE BRANDS LLC (US) 2025-10-15 EP claimed
EP-4599698-A1 PRODUCTS COMPRISING SENSORY AGENTS Nicoventures Trading Limited (GB) 2025-08-13 EP claimed
EP-4192422-B1 COOLING SENSATION COMPOSITIONS GIVAUDAN SA (CH) 2025-06-11 EP claimed
WO-2025078256-A1 COMPOSITION GIVAUDAN SA (CH) 2025-04-17 WO claimed
WO-2025068299-A1 AEROSOL-GENERATING ARTICLE, DEVICE AND SYSTEM JT INTERNATIONAL SA (CH) 2025-04-03 WO claimed
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 WO claimed
CN-118873543-A Aerosol matrix, application thereof and aerosol generating device 深圳芳芯科技有限公司 2024-11-01 CN claimed
US-7482378-B2 Physiological cooling compositions MILLENIUM SPECIALTY CHEMICALS, INC. (US) 2009-01-27 US claimed
EP-2008530-A1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions Symrise GmbH & Co. KG (DE) 2008-12-31 EP claimed
US-20080311232-A1 Cooling Compounds GIVAUDAN, SA (CH) 2008-12-18 US claimed
WO-2008151460-A2 COOLING COMPOUNDS GIVAUDAN SA (CH) 2008-12-18 WO claimed
US-20080293821-A1 Cooling compositions MOZA ASHOK K 2008-11-27 US claimed
WO-2008138162-A1 COMPOSITIONS AND THEIR USE GIVAUDAN SA (CH) 2008-11-20 WO claimed
US-20080262613-A1 Biocompatible, Biodegradable Polyurethane Materials With Controlled Hydrophobic to Hydrophilic Ratio SYNTHES USA, LLC 2008-10-23 US claimed
CN-1938265-A Physiological cooling composition containing highly purified ethyl N- [ [ 5-methyl-2- (1-methylethyl) cyclohexyl ] carbonyl ] glycinate MILLENNIUM SPECIALTY CHEM INC (US) 2007-03-28 CN claimed
US-4178459-A N-Substituted paramenthane carboxamides WILKINSON SWORD LIMITED (GB) 1979-12-11 US claimed
US-4060091-A N-SUBSTITUTED P-MENTHANE CARBOXAMID WILKINSON SWORD LIMITED (EN) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311232-A1 Cooling Compounds MAL2, NCOR2, NCOA2 TRPM8 272/4885EPHX1 1684/4885EPHX2 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.