Trans-4,4'-Dihydroxystilbene

Trans-4,4'-Dihydroxystilbene

SCHEMBL145659

Oc1ccc(C=Cc2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.74
KDM4E B2RXH2 4/20 0.74
ALDH1A1 P00352 4/20 0.74
MAPT P10636 4/20 0.74
CA12 O43570 4/20 0.74
CA1 P00915 4/20 0.74
CA2 P00918 4/20 0.74
CA3 P07451 4/20 0.74
CA4 P22748 4/20 0.74
CA5A P35218 4/20 0.74
CA9 Q16790 4/20 0.74
CA14 Q9ULX7 4/20 0.74
CA5B Q9Y2D0 4/20 0.74
TYR P14679 4/20 0.74
CYP2C9 P11712 3/20 0.74
CA6 P23280 3/20 0.74
CA7 P43166 3/20 0.74
MEN1 O00255 3/20 0.74
LMNA P02545 3/20 0.74
CYP3A4 P08684 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6266983 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9678794 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL6266987 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
Trans-4,4'-Dihydroxystilbene SCHEMBL491346 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9678787 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL6266989 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9680089 0.91 ESR1 (0.65) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9680087 0.91 ESR1 (0.65) APPKDM4EALDH1A1MAPTCA12
(E)-4-Styrylphenol SCHEMBL27993 0.88 APP (0.61) APPKDM4EALDH1A1MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4206 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
EP-4493220-A2 BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS Yale University (US) 2025-01-22 EP claimed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO claimed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US claimed
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 EP claimed
US-11951116-B2 Vaginal composition and use thereof SINGAPORE ZE&ZINTERNATIONAL PTE. LTD (SG) 2024-04-09 US claimed
CN-117413000-A Polyurethane product and method for producing a polyurethane product 陶氏环球技术有限责任公司 2024-01-16 CN claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0001910-B1 PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF MONSANTO COMPANY (US) 1981-09-02 EP claimed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US claimed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP claimed
US-4141874-A Fluorine-containing elastomeric copolymers, process for preparing the same and composition containing the same DAIKIN KOGYO CO., LTD. (JP) 1979-02-27 US claimed