Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | CA12 | O43570 | 4/20 | 0.74 |
| ▸ | CA1 | P00915 | 4/20 | 0.74 |
| ▸ | CA2 | P00918 | 4/20 | 0.74 |
| ▸ | CA3 | P07451 | 4/20 | 0.74 |
| ▸ | CA4 | P22748 | 4/20 | 0.74 |
| ▸ | CA5A | P35218 | 4/20 | 0.74 |
| ▸ | CA9 | Q16790 | 4/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.74 |
| ▸ | TYR | P14679 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.74 |
| ▸ | CA6 | P23280 | 3/20 | 0.74 |
| ▸ | CA7 | P43166 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678794 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| SCHEMBL6266987 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL145659 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL491346 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| SCHEMBL9678787 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| SCHEMBL6266989 | 1.00 | APP (0.74) | APPKDM4EALDH1A1MAPTCA12 | |
| SCHEMBL9680089 | 0.91 | ESR1 (0.65) | APPKDM4EALDH1A1MAPTCA12 | |
| SCHEMBL9680087 | 0.91 | ESR1 (0.65) | APPKDM4EALDH1A1MAPTCA12 | |
| (E)-4-Styrylphenol SCHEMBL27993 | 0.88 | APP (0.61) | APPKDM4EALDH1A1MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| US-20090041666-A1 | Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof | NEUROPTIX CORPORATION | 2009-02-12 | — | — | US | disclosed |
| US-20090041666-A1 | Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof | NEUROPTIX CORPORATION | 2009-02-12 | — | — | US | disclosed |
| WO-2008144065-A1 | OPHTHALMIC FORMULATIONS OF AMYLOID- CONTRAST AGENTS AND METHODS OF USE THEREOF | NEUROPTIX CORPORATION (US) | 2008-11-27 | — | — | WO | disclosed |
| US-7449282-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-7449282-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| WO-2005085189-A2 | ANALOGUES OF CONGO RED AND EVALUATION OF THEIR ANTI-PRION ACTIVITY | MEDICAL RESEARCH COUNCIL (GB) | 2005-09-15 | — | — | WO | disclosed |
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0391204-A2 | Process for preparing moulded articles of polymers with E-configurated stilbene moieties | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041666-A1 | Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof | APP, IAPP, CRYAB | APP 1/4885KDM4E 4699/4885ALDH1A1 3168/4885 |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | APP 2941/4885KDM4E 1414/4885ALDH1A1 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.