Trans-4,4'-Dihydroxystilbene

Trans-4,4'-Dihydroxystilbene

SCHEMBL491346

Oc1ccc(/C=C/c2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.74
KDM4E B2RXH2 4/20 0.74
ALDH1A1 P00352 4/20 0.74
MAPT P10636 4/20 0.74
CA12 O43570 4/20 0.74
CA1 P00915 4/20 0.74
CA2 P00918 4/20 0.74
CA3 P07451 4/20 0.74
CA4 P22748 4/20 0.74
CA5A P35218 4/20 0.74
CA9 Q16790 4/20 0.74
CA14 Q9ULX7 4/20 0.74
CA5B Q9Y2D0 4/20 0.74
TYR P14679 4/20 0.74
CYP2C9 P11712 3/20 0.74
CA6 P23280 3/20 0.74
CA7 P43166 3/20 0.74
MEN1 O00255 3/20 0.74
LMNA P02545 3/20 0.74
CYP3A4 P08684 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6266983 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9678794 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL6266987 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
Trans-4,4'-Dihydroxystilbene SCHEMBL145659 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9678787 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL6266989 1.00 APP (0.74) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9680089 0.91 ESR1 (0.65) APPKDM4EALDH1A1MAPTCA12
SCHEMBL9680087 0.91 ESR1 (0.65) APPKDM4EALDH1A1MAPTCA12
(E)-4-Styrylphenol SCHEMBL27993 0.88 APP (0.61) APPKDM4EALDH1A1MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US claimed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO claimed
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 EP claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
CN-115232036-A Stilbene polyphenol taurate, preparation method and application thereof 南通大学 2022-10-25 CN claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed
US-4877711-A DURABLE PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
EP-0001910-B1 PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF MONSANTO COMPANY (US) 1981-09-02 EP claimed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US claimed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP claimed
US-4141874-A Fluorine-containing elastomeric copolymers, process for preparing the same and composition containing the same DAIKIN KOGYO CO., LTD. (JP) 1979-02-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB APP 1117/4885KDM4E 4637/4885ALDH1A1 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.