Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566424 | 0.95 | KDM4E (0.36) | FDPSKDM4ETP53CYP3A4MAPT | |
| SCHEMBL14566422 | 0.93 | KDM4E (0.38) | FDPSKDM4ETP53CYP3A4MAPT | |
| SCHEMBL14566351 | 0.89 | HDAC3 (0.34) | ALDH1A1MEN1NPC1CYP1A2RAB9A | |
| SCHEMBL14566358 | 0.85 | MEN1 (0.33) | ALDH1A1MEN1NPC1CYP1A2RAB9A | |
| SCHEMBL24304548 | 0.83 | NOS3 (0.39) | FDPSTP53MAPTACHECYP4F2 | |
| SCHEMBL14566356 | 0.83 | TSHR (0.33) | CYP3A4MAPTTSHRALDH1A1HDAC3 | |
| SCHEMBL14566506 | 0.83 | — | — | |
| SCHEMBL14566436 | 0.82 | MEN1 (0.31) | ALDH1A1MEN1NPC1CYP1A2RAB9A | |
| SCHEMBL14566354 | 0.82 | MEN1 (0.31) | ALDH1A1MEN1NPC1CYP1A2RAB9A | |
| SCHEMBL14566406 | 0.82 | MEN1 (0.33) | ALDH1A1MEN1NPC1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027248-A2 | 3', 5' - CYCLIC NUCLEOSIDE ANALOGUES FOR TREATMENT OF HCV | VALEANT RESEARCH & DEVELOPMENT (US) | 2007-03-08 | — | — | WO | disclosed |