Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 5/20 | 0.32 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695618 | 0.85 | NOS3 (0.40) | NOS3NOS1NOS2CES1ALDH1A1 | |
| SCHEMBL14566355 | 0.83 | FDPS (0.32) | ALDH1A1FDPSACHECYP4F2CYP4A11 | |
| SCHEMBL13523351 | 0.83 | NOS3 (0.39) | NOS3NOS1NOS2CES1ALDH1A1 | |
| SCHEMBL26688754 | 0.81 | KMT2A (0.46) | CES1ALDH1A1TDP1CES2FAAH | |
| SCHEMBL26711090 | 0.81 | KMT2A (0.46) | CES1ALDH1A1TDP1CES2FAAH | |
| SCHEMBL26711078 | 0.81 | KMT2A (0.46) | CES1ALDH1A1TDP1CES2FAAH | |
| SCHEMBL3866692 | 0.80 | NOS3 (0.43) | NOS3NOS1NOS2CES1ALDH1A1 | |
| SCHEMBL14566424 | 0.78 | KDM4E (0.36) | FDPSACHECYP4F2CYP4A11TP53 | |
| SCHEMBL26711087 | 0.78 | ACACB (0.54) | FDPSFAAH | |
| SCHEMBL26711094 | 0.78 | ACACB (0.54) | FDPSFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022066916-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2022-03-31 | — | — | WO | disclosed |