Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798271 | 0.81 | MAPT (0.56) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL11798305 | 0.79 | MAPT (0.54) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL17249971 | 0.79 | MAPT (0.54) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL8666029 | 0.75 | IDO1 (0.64) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL29562554 | 0.75 | IDO1 (0.64) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL6502800 | 0.71 | BCHE (0.76) | HTTKMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL14567007 | 0.69 | KMT2A (0.51) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL11864498 | 0.67 | IDO1 (0.46) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL14567006 | 0.67 | RAB9A (0.49) | MAPTHTTKMT2ALMNAMEN1 | |
| SCHEMBL354514 | 0.66 | MEN1 (0.56) | MAPTHTTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026041-A2 | COMPUESTOS QUINÓNICOS ANTITUMORALES Y SUS DERIVADOS, PROCEDIMIENTO DE OBTENCIÓN Y SUS APLICACIONES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2007-03-08 | — | — | WO | disclosed |