Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.76 |
| ▸ | ACHE | P22303 | 3/20 | 0.76 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328047 | 0.83 | ACHE (0.57) | BCHEACHEMALT1KDM4EGAA | |
| SCHEMBL11798271 | 0.79 | MAPT (0.56) | BCHEACHEKDM4EGAAHTT | |
| SCHEMBL17249971 | 0.78 | MAPT (0.54) | BCHEACHEKDM4EGAAHTT | |
| SCHEMBL11798305 | 0.78 | MAPT (0.54) | BCHEACHEKDM4EGAAHTT | |
| SCHEMBL918426 | 0.74 | KDM4E (0.66) | BCHEACHEMALT1KDM4EGAA | |
| SCHEMBL7840653 | 0.73 | GAA (0.68) | BCHEACHEMALT1KDM4EGAA | |
| SCHEMBL924357 | 0.72 | ACHE (0.68) | BCHEACHEKDM4EGAABACE1 | |
| SCHEMBL10768489 | 0.71 | NSD2 (0.64) | GAAHTTKMT2AMAPK1SIGMAR1 | |
| SCHEMBL2840739 | 0.71 | ACHE (0.70) | BCHEACHEKDM4EGAABACE1 | |
| SCHEMBL6335815 | 0.71 | HTT (0.67) | BCHEACHEKDM4EGAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | CLINICAL DATA, INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | NQO1, DPYD, NQO2 | BCHE 4148/4885ACHE 3776/4885MALT1 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.