Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429352 | 0.81 | CYP2D6 (0.31) | THRBHSD17B10 | |
| SCHEMBL14429341 | 0.81 | CYP2D6 (0.31) | THRBHSD17B10 | |
| SCHEMBL14568800 | 0.80 | PPP5C (0.38) | PPP5CALDH1A1CYP3A4MAPTTHRB | |
| SCHEMBL14569023 | 0.79 | HSD17B10 (0.40) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 | |
| SCHEMBL14568665 | 0.76 | ALDH1A1 (0.36) | PPP5CALDH1A1CYP3A4MAPTTHRB | |
| SCHEMBL14429337 | 0.74 | CYP2D6 (0.31) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 | |
| SCHEMBL1627641 | 0.71 | CA2 (0.42) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 | |
| SCHEMBL1626249 | 0.71 | CA2 (0.42) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 | |
| SCHEMBL1627640 | 0.71 | CA2 (0.42) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 | |
| SCHEMBL1626250 | 0.71 | CA2 (0.42) | ALDH1A1CYP3A4MAPTTHRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025043-A2 | SEVEN-MEMBERED RING NUCLEOSIDES | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |