Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.77 |
| ▸ | PDE4A | P27815 | 12/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.77 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360400 | 0.76 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7359192 | 0.76 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7355649 | 0.76 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7368338 | 0.76 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7333823 | 0.76 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL10780014 | 0.74 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL14597364 | 0.74 | PDE4A (0.57) | PDE4BPDE4APDE4CPDE4DCYP11B1 | |
| SCHEMBL7358558 | 0.74 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7369703 | 0.73 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL7366624 | 0.73 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196080-B2 | Respiratory system disordeers; chronic obstructive pulminary disease | ASTELLAS PHARMA INC. (JP) | 2007-03-27 | — | — | US | disclosed |