Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598813 | 0.76 | MAPT (0.50) | MAPTLMNAHRH3NPC1RAB9A | |
| SCHEMBL4940440 | 0.76 | DRD2 (0.40) | LMNAKMT2ACDK4CCND1MEN1 | |
| SCHEMBL12424155 | 0.76 | MAPT (0.40) | MAPTLMNAGFERNPC1RAB9A | |
| SCHEMBL1048007 | 0.76 | MAPT (0.40) | MAPTLMNAGFERNPC1RAB9A | |
| SCHEMBL1048008 | 0.76 | MAPT (0.40) | MAPTLMNAGFERNPC1RAB9A | |
| SCHEMBL4940436 | 0.76 | DRD2 (0.40) | LMNAKMT2ACDK4CCND1MEN1 | |
| SCHEMBL13380438 | 0.75 | MAPK1 (0.50) | MAPTLMNAHRH3L3MBTL1CDK4 | |
| SCHEMBL14570543 | 0.75 | HRH3 (0.48) | LMNAHRH3L3MBTL1CDK4CCND1 | |
| Fumaric Acid SCHEMBL27669967 | 0.75 | MDM2 (0.43) | MAPTLMNAKMT2AL3MBTL1CDK4 | |
| SCHEMBL24123783 | 0.73 | SIGMAR1 (0.37) | MAPTLMNAKMT2ACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196080-B2 | Respiratory system disordeers; chronic obstructive pulminary disease | ASTELLAS PHARMA INC. (JP) | 2007-03-27 | — | — | US | disclosed |