Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007031 | 0.82 | KDM4E (0.30) | KDM4E | |
| SCHEMBL14572068 | 0.77 | KDM4E (0.37) | KDM4E | |
| SCHEMBL14276910 | 0.75 | KDM4E (0.40) | KDM4E | |
| SCHEMBL14685157 | 0.68 | GPR139 (0.37) | — | |
| SCHEMBL16160353 | 0.68 | BRAF (0.39) | KDM4E | |
| SCHEMBL23486188 | 0.66 | — | — | |
| SCHEMBL19382370 | 0.63 | NOTUM (0.33) | — | |
| SCHEMBL19171558 | 0.62 | — | — | |
| SCHEMBL12970012 | 0.62 | ALOX12 (0.47) | KDM4E | |
| SCHEMBL24131213 | 0.61 | SMN1; SMN2 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196095-B2 | (Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds | MERCK & CO., INC. (US) | 2007-03-27 | — | — | US | disclosed |