Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044635 | 0.87 | GAA (0.45) | LMNAHTTGAAPOLBMAPT | |
| SCHEMBL1045936 | 0.86 | LMNA (0.43) | LMNAHTTGAAPOLBMAPT | |
| SCHEMBL1043686 | 0.85 | CHRM1 (0.45) | LMNAHTTGAAMAPTCHRM1 | |
| SCHEMBL1044962 | 0.83 | GAA (0.51) | LMNAHTTGAAPOLBMAPT | |
| SCHEMBL1044491 | 0.83 | CHRM1 (0.46) | LMNAMAPTCHRM1KDM4EALDH1A1 | |
| SCHEMBL11948638 | 0.82 | LMNA (0.43) | LMNAKMT2ACHRM1CCR2KDM4E | |
| SCHEMBL1042896 | 0.81 | LMNA (0.48) | LMNAHTTGAAMAPTCHRM1 | |
| SCHEMBL1045221 | 0.81 | GAA (0.44) | LMNAHTTGAAPOLBMAPT | |
| SCHEMBL1045775 | 0.81 | METTL3 (0.50) | LMNAHTTGAAMAPTCHRM1 | |
| SCHEMBL1045768 | 0.81 | GAA (0.44) | LMNAHTTGAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |