SCHEMBL1457604

SCHEMBL1457604

CC(C)(C)c1cccc2sc(SN)nc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TDP1 Q9NUW8 4/20 0.34
CYP3A4 P08684 3/20 0.34
LMNA P02545 2/20 0.33
PDPK1 O15530 1/20 0.33
CA2 P00918 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDE10A Q9Y233 1/20 0.33
HPGD P15428 2/20 0.33
FBP1 P09467 2/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
DRD2 P14416 1/20 0.33
ALOX15 P16050 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
DRD1 P21728 1/20 0.33
MC5R P33032 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536259 0.86 ALDH1A1 (0.34) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL8531857 0.84 CYP3A4 (0.33) ALDH1A1TDP1CYP3A4HPGDFBP1
SCHEMBL20943483 0.79
SCHEMBL11607734 0.78 ALDH1A1 (0.61) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL29515259 0.78 ALDH1A1 (0.61) ALDH1A1TDP1CYP3A4LMNASMN1; SMN2
SCHEMBL17489174 0.78 TNF (0.40) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL9244622 0.77 ALDH1A1 (0.34) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL28392628 0.76 CASR (0.40) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL19008541 0.76 CA2 (0.38) ALDH1A1TDP1CYP3A4LMNAPDPK1
SCHEMBL10204224 0.76 ALDH1A1 (0.41) ALDH1A1TDP1CYP3A4LMNAPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285682-A Degradable adjustable temporary plugging agent and preparation method thereof 中国石油天然气集团有限公司 2023-12-26 CN claimed
CN-112630262-B Test method for detecting activity of vulcanization activator 华东理工大学 2023-12-22 CN claimed
CN-112225959-A High-wear-resistance low-heat-generation synthetic natural rubber composite material and preparation method and application thereof 中国科学院长春应用化学研究所 2021-01-15 CN claimed
CN-110408209-A A kind of halogen-free flame retardant sheath material Qin Zaizhen 2019-11-05 CN claimed
CN-106948082-B High density imitation inner leather 平阳盛兴无纺布有限公司 2019-02-19 CN claimed
CN-109306093-A A kind of resist bending shielding enhanced rubber CABLE MATERIALS 王亚南 2019-02-05 CN claimed
CN-109265761-A Burning non-dripping rubber and preparation method thereof 安徽建筑大学 2019-01-25 CN claimed
CN-108864484-A N tert butyl benzothiazole 2 sulfenamide lotion and preparation method thereof 济源和瑞环保科技有限公司 2018-11-23 CN claimed
WO-2014012979-A2 LATEX COMPOSITION SOBELTEC (BE) 2014-01-23 WO claimed
US-8431667-B2 Guayule natural rubber latex thin film articles YULEX CORPORATION (US) 2013-04-30 US claimed
EP-0690091-B1 Improvements in and relating to the reclaiming of natural and synthetic rubbers SEKHAR B C SDN BHD (MY) 1999-09-15 EP claimed
EP-0569995-B1 Scorch retardant compositions for peroxide curable elastomers CRAY VALLEY SA (FR) 1998-12-16 EP claimed
US-5792303-A COMBINATION OF A FLUID CARRIER THAT REMAINS SUBSTANTIALLY PRESENT DURING THE CURING OF AN ADHESIVE COMPOSITION AND AN ACTIVE COMPONENT CAPABLE OF PROMOTING THE CURE AND/OR ENHANCING ADHESION WHILE BEING MISCIBLE IN THE FLUID CARRIER LOCTITE CORPORATION (US) 1998-08-11 US claimed
EP-0785865-A4 NON-VOLATILE ADHESIVE PROMOTER COMPOSITION FOR CURING ADHESIVES LOCTITE CORP (US) 1998-01-07 EP claimed
EP-0785865-A1 NON-VOLATILE ADHESIVE PROMOTER COMPOSITION FOR CURING ADHESIVES LOCTITE CORPORATION (US) 1997-07-30 EP claimed
EP-0748837-A1 Improvements in and relating to the reclaiming of naturel and synthetic rubbers STI-K POLYMERS SDN BHD (MY) 1996-12-18 EP claimed
US-5567266-A A CARRIER, AN ESTER WITH ADHESIVE PROMOTER AND AMINE COMPOUND LOCTITE CORPORATION (US) 1996-10-22 US claimed
WO-1996011799-A1 NON-VOLATILE ADHESIVE PROMOTER COMPOSITION FOR CURING ADHESIVES LOCTITE CORPORATION (US) 1996-04-25 WO claimed
EP-0504320-B1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES UNIROYAL CHEM CO INC (US) 1994-09-21 EP claimed
EP-0569995-A1 Scorch retardant compositions for peroxide curable elastomers CRAY VALLEY SA (FR) 1993-11-18 EP claimed