Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1457638 | 1.00 | PRKCA (0.38) | PRKCASLC7A5BTN3A1COMTALDH1A1 | |
| SCHEMBL19235874 | 0.84 | PRKCA (0.40) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL14648399 | 0.84 | PRKCA (0.40) | PRKCABTN3A1ALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL19209658 | 0.82 | GRIN2D (0.39) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL16017805 | 0.81 | DPP4 (0.39) | PRKCADPP4 | |
| SCHEMBL6840505 | 0.80 | PRKCA (0.40) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL19420430 | 0.79 | SLC7A5 (0.42) | SLC7A5COMTPSMB5SLC15A1DPP4 | |
| SCHEMBL10253729 | 0.79 | PRKCA (0.42) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL681950 | 0.78 | PRKCA (0.46) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL13577876 | 0.78 | ALOX15 (0.41) | SLC7A5COMTPSMB5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038207-A1 | PHOSPHORUS-CONTAINING THYROID HORMONE RECEPTOR AGONISTS AND METHODS OF USE | METABASIS THERAPEUTICS, INC. (US) | 2011-03-31 | — | — | WO | disclosed |