Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CCR1 | P32246 | 5/20 | 0.60 |
| ▸ | CCR8 | P51685 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142651 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL6513577 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL8313 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL4447950 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL724138 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL3862777 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL15052618 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL4858817 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL10789328 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1003398 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987446-B2 | Bimetallic complexes and the use thereof in producing diaryl carbonate | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20130018186-A1 | BIMETALLIC COMPLEXES AND THE USE THEREOF IN PRODUCING DIARYL CARBONATE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018186-A1 | BIMETALLIC COMPLEXES AND THE USE THEREOF IN PRODUCING DIARYL CARBONATE | SOD1, BMI1, SCO2 | LMNA 4073/4885CYP3A4 522/4885CCR1 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.