SCHEMBL14577136

SCHEMBL14577136

CC(C)n1nccc1NC(N)=S

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 2/20 0.45
NR3C2 P08235 1/20 0.43
CTSK P43235 2/20 0.38
KMT2A Q03164 3/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.34
TYR P14679 1/20 0.34
TSHR P16473 1/20 0.34
TAS2R38 P59533 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23252604 0.75 L3MBTL1 (0.39) L3MBTL1NR3C2CTSKKMT2AALDH1A1
SCHEMBL14576642 0.74 EPHX1 (0.53) MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL12073995 0.69 MAPK14 (0.42) MAPTGAA
SCHEMBL2307447 0.67 NR3C2 (0.48) L3MBTL1MAPTNR3C2HTTALDH1A1
SCHEMBL1628593 0.66
SCHEMBL1487464 0.63
SCHEMBL22334277 0.62
SCHEMBL21817999 0.62
SCHEMBL4365364 0.62
SCHEMBL19737896 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2731430-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-04-03 EP disclosed
EP-2731430-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-04-03 EP disclosed
US-9440964-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-09-13 US disclosed
US-9440964-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-09-13 US disclosed
US-9440964-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-09-13 US disclosed
US-20150196033-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (IN) 2015-07-16 US disclosed
US-20150196033-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (IN) 2015-07-16 US disclosed
US-20150196033-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (IN) 2015-07-16 US disclosed
US-20150197514-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2015-07-16 US disclosed
US-20150197514-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2015-07-16 US disclosed
US-20150197514-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2015-07-16 US disclosed
CN-103826452-A Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC 2014-05-28 CN disclosed
WO-2014011429-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-01-16 WO disclosed
US-20130019348-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-01-17 US disclosed
US-20130019348-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-01-17 US disclosed
WO-2013009791-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-01-17 WO disclosed
US-20130019348-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150196033-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, CAT L3MBTL1 3362/4885MAPT 2932/4885NR3C2 4710/4885
US-20150197514-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, CAT L3MBTL1 3362/4885MAPT 2932/4885NR3C2 4710/4885
US-20130019348-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, CAT L3MBTL1 3362/4885MAPT 2932/4885NR3C2 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.