Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579483 | 0.84 | CYP3A4 (0.43) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14579484 | 0.81 | TSHR (0.46) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5403760 | 0.75 | TSHR (0.56) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13893457 | 0.70 | PRKCA (0.48) | TSHRCYP3A4CYP1A2CYP2C9HIF1A | |
| SCHEMBL9041279 | 0.69 | L3MBTL1 (0.57) | TSHRALPLGLAALPIALPG | |
| SCHEMBL7590598 | 0.69 | L3MBTL1 (0.57) | TSHRALPLGLAALPIALPG | |
| SCHEMBL13884854 | 0.69 | PRKCA (0.49) | TSHRCYP3A4CYP1A2CYP2C9HIF1A | |
| SCHEMBL18556835 | 0.68 | CYP3A4 (0.54) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5488348 | 0.67 | CYP3A4 (0.68) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11037999 | 0.67 | CYP3A4 (0.68) | TSHRCYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179308-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179308-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-7172634-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
| US-7172634-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-06 | — | — | US | disclosed |