SCHEMBL14580374

SCHEMBL14580374

Cc1ccc(NC(=O)c2ccc(C(=O)Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 12/20 1.00
▸ NPC1 O15118 11/20 1.00
▸ SMN1; SMN2 Q16637 6/20 0.81
▸ MAPT P10636 3/20 0.81
▸ MEN1 O00255 2/20 0.67
▸ LMNA P02545 2/20 0.67
▸ KMT2A Q03164 2/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ NAMPT P43490 1/20 0.67
▸ MCL1 Q07820 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ ALDH1A1 P00352 3/20 0.64
▸ GAA P10253 1/20 0.64
▸ PKM P14618 2/20 0.63
▸ TDP1 Q9NUW8 2/20 0.63
▸ POLB P06746 1/20 0.63
▸ APEX1 P27695 1/20 0.63
▸ TP53 P04637 2/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ ALOX15 P16050 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27181403 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL822378 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL15214321 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL12310125 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL25491824 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL21185831 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL25970267 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL17066707 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL15214314 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL12200275 0.92 RAB9A (0.85) RAB9ANPC1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9455067-B2 Low dielectric materials ITEQ CORPORATION (TW) 2016-09-27 — — US disclosed
US-9455067-B2 Low dielectric materials ITEQ CORPORATION (TW) 2016-09-27 — — US disclosed
US-20160148719-A1 LOW DIELECTRIC MATERIALS ITEQ CORPORATION (TW) 2016-05-26 — — US disclosed
US-20160148719-A1 LOW DIELECTRIC MATERIALS ITEQ CORPORATION (TW) 2016-05-26 — — US disclosed
US-20070026225-A1 Primer composition for high temperature belts EASTMAN KODAK COMPANY 2007-02-01 — — US disclosed
US-20070026225-A1 Primer composition for high temperature belts EASTMAN KODAK COMPANY 2007-02-01 — — US disclosed
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