SCHEMBL822378

SCHEMBL822378

Cc1ccc(NC(=O)c2ccc(C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 12/20 1.00
NPC1 O15118 11/20 1.00
SMN1; SMN2 Q16637 6/20 0.81
MAPT P10636 3/20 0.81
MEN1 O00255 2/20 0.67
LMNA P02545 2/20 0.67
KMT2A Q03164 2/20 0.67
KDM4E B2RXH2 2/20 0.67
NAMPT P43490 1/20 0.67
MCL1 Q07820 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
ALDH1A1 P00352 3/20 0.64
GAA P10253 1/20 0.64
PKM P14618 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
POLB P06746 1/20 0.63
APEX1 P27695 1/20 0.63
TP53 P04637 2/20 0.63
MAPK1 P28482 1/20 0.63
ALOX15 P16050 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15214321 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL12310125 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL27181403 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL14580374 1.00 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL25491824 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL21185831 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL25970267 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL17066707 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL15214314 0.94 RAB9A (0.88) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL676148 0.92 RAB9A (0.85) RAB9ANPC1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020119836-A1 PROCESS FOR PREPARING OBETICHOLIC ACID FARMAK, A.S. (CZ) 2020-06-18 WO claimed
CN-118420484-B Method for preparing amide compounds 四川大学 2024-08-30 CN disclosed
CN-118420484-A Method for preparing amide compounds 四川大学 2024-08-02 CN disclosed
US-20240241403-A1 POLARIZER AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-07-18 US disclosed
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
CN-115304506-B Preparation method of secondary amide compound by activating primary amide through boron salt catalysis 中国人民解放军国防科技大学 2023-11-14 CN disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-7183342-B2 Flame-retardant aromatic polycarbonate resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-02-27 US disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 US disclosed
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 US disclosed
US-20070042295-A1 Optical data carrier comprising a polymeric network in the information layer LANXESS DEUTSCHLAND GMBH (DE) 2007-02-22 US disclosed
US-20070042295-A1 Optical data carrier comprising a polymeric network in the information layer LANXESS DEUTSCHLAND GMBH (DE) 2007-02-22 US disclosed
US-7157548-B2 Crosslinked sulfonated polyimide films HANYANG HAK WON CO., LTD. (KR) 2007-01-02 US disclosed
US-7157548-B2 Crosslinked sulfonated polyimide films HANYANG HAK WON CO., LTD. (KR) 2007-01-02 US disclosed
WO-2003007954-A2 SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2003-01-30 WO disclosed
US-5364912-A Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid THE DOW CHEMICAL COMPANY (US) 1994-11-15 US disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed