SCHEMBL14581972

SCHEMBL14581972

COCC(C)Nc1cc(-c2ccnc(Nc3ccc(Cl)cc3)n2)ccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CAMK2D Q13557 6/20 0.56
▸ PIK3CA P42336 3/20 0.55
▸ PIK3CB P42338 3/20 0.55
▸ PIK3CG P48736 3/20 0.55
▸ PLK1 P53350 1/20 0.54
▸ SMG1 Q96Q15 2/20 0.50
▸ CDK2 P24941 4/20 0.49
▸ JAK2 O60674 1/20 0.49
▸ EGFR P00533 1/20 0.49
▸ PTK2B Q14289 1/20 0.49
▸ CLK4 Q9HAZ1 2/20 0.48
▸ CLK1 P49759 1/20 0.48
▸ DYRK1A Q13627 1/20 0.48
▸ DYRK1B Q9Y463 1/20 0.48
▸ MAPT P10636 2/20 0.47
▸ CSNK2A1 P68400 1/20 0.47
▸ NPC1 O15118 2/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ CDK5 Q00535 2/20 0.46
▸ CDK5R1 Q15078 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6107479 0.89 CSNK2A1 (0.62) CAMK2DPIK3CAPIK3CBPIK3CGPLK1
SCHEMBL2403389 0.89 CAMK2D (0.52) CAMK2DPIK3CAPIK3CBPIK3CGSMG1
SCHEMBL6488247 0.86 CDK2 (0.47) CAMK2DPIK3CAPIK3CBPIK3CGPLK1
SCHEMBL2389030 0.81 CSNK2A1 (0.56) CAMK2DPIK3CAPIK3CBPIK3CGPLK1
SCHEMBL6106440 0.80 MAPT (0.55) CAMK2DPIK3CAPIK3CBPIK3CGPLK1
SCHEMBL2390633 0.78 CDK2 (0.47) CDK2CLK4CLK1DYRK1ADYRK1B
SCHEMBL3476018 0.77 MAPT (0.47) CAMK2DPIK3CAPIK3CBPIK3CGSMG1
SCHEMBL2388443 0.76 MAPK14 (0.41) CAMK2DPIK3CAPIK3CBPIK3CGSMG1
SCHEMBL6476621 0.75 CDK1 (0.61) CAMK2DSMG1CDK2EGFRCLK4
SCHEMBL6482454 0.75 CDK1 (0.61) CAMK2DSMG1CDK2EGFRCLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389442-B2 N-phenyl-′(4-pyridyl)-azinyl!amine derivatives as plant protection agents SYNGENTA CROP PROTECTION LLC (US) 2013-03-05 — — US disclosed
US-8389442-B2 N-phenyl-′(4-pyridyl)-azinyl!amine derivatives as plant protection agents SYNGENTA CROP PROTECTION LLC (US) 2013-03-05 — — US disclosed
US-20070032490-A1 N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents SYNGENTA CROP PROTECTION, INC. 2007-02-08 — — US disclosed
US-20070032490-A1 N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents SYNGENTA CROP PROTECTION, INC. 2007-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032490-A1 N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents CYP1A1, NAT1, AKR7A2 CAMK2D 3643/4885PIK3CA 1184/4885PIK3CB 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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