Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 10/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403389 | 0.88 | CAMK2D (0.52) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL14581972 | 0.77 | CAMK2D (0.56) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL2330123 | 0.77 | PLK1 (0.56) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL6107479 | 0.77 | CSNK2A1 (0.62) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL2390633 | 0.73 | CDK2 (0.47) | MAPTCDK2CDK4CCNA2MTOR | |
| SCHEMBL2333324 | 0.71 | CDK2 (0.53) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL2326806 | 0.71 | AAK1 (0.36) | MAPTCDK2CDK4CCNA2MTOR | |
| SCHEMBL2389030 | 0.71 | CSNK2A1 (0.56) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL27843897 | 0.70 | DYRK1A (0.49) | MAPTCAMK2DCSNK2A1CDK2CDK4 | |
| SCHEMBL6106440 | 0.70 | MAPT (0.55) | MAPTCAMK2DCSNK2A1CDK2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273759-B2 | Fungicide heterocyclyl-pyrimidinyl-amino derivatives | BAYER CROPSCIENCE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | PAH, CYP4X1, PRXL2A | MAPT 4430/4885CAMK2D 4240/4885CSNK2A1 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.