Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29781391 | 1.00 | P2RX1 (0.56) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL10607741 | 0.90 | P2RX1 (0.63) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL23419298 | 0.84 | P2RX1 (0.69) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL574259 | 0.82 | HDAC3 (0.63) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL30288530 | 0.82 | HDAC3 (0.63) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL29372818 | 0.82 | HDAC3 (0.63) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL23419292 | 0.82 | RXFP1 (0.66) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL14582007 | 0.81 | P2RX1 (0.65) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL10347262 | 0.77 | P2RX1 (0.56) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL14582016 | 0.76 | RXFP1 (0.66) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727975-A | Antiandrogen receptor/AKR 1C3 inhibitors | 加利福尼亚大学董事会 | 2022-07-08 | — | — | CN | disclosed |
| EP-1328507-B1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | UNIV NEW YORK STATE RES FOUND (US) | 2007-03-14 | — | — | EP | disclosed |