Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 5/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583989 | 0.88 | NPY4R (0.40) | KISS1RNPY1RNPY2RNPY5R | |
| SCHEMBL14583981 | 0.86 | KLKB1 (0.47) | KLKB1PADI4PSMB1PSMB5PSMB2 | |
| SCHEMBL14090268 | 0.79 | CA1 (0.49) | KLKB1PSMB1PSMB5PSMB2PSMB8 | |
| SCHEMBL12214556 | 0.79 | NPY4R (0.50) | KISS1RNPY1RNPY2RNPY5R | |
| SCHEMBL14531580 | 0.78 | FNTA (0.47) | KISS1R | |
| SCHEMBL24109806 | 0.75 | NPY4R (0.54) | KISS1RNPY1RNPY2RNPY5R | |
| SCHEMBL14090280 | 0.73 | NPY1R (0.50) | KLKB1PSMB1PSMB5PSMB2PSMB8 | |
| SCHEMBL22503596 | 0.73 | MME (0.52) | — | |
| SCHEMBL20540754 | 0.73 | MME (0.52) | — | |
| SCHEMBL22503737 | 0.73 | MME (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |