Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14585956 | 0.82 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Bicarbonate SCHEMBL10377652 | 0.82 | ALDH1A1 (0.67) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10961565 | 0.82 | KDM4E (0.54) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL26193813 | 0.82 | KDM4E (0.75) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL14615774 | 0.82 | GPR174 (0.52) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL18864181 | 0.82 | KDM4E (0.51) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL18864182 | 0.81 | KDM4E (0.50) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL18864179 | 0.81 | KDM4E (0.50) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL18864183 | 0.81 | KDM4E (0.50) | HRH3LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL18864170 | 0.81 | KDM4E (0.50) | HRH3LMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176206-B2 | Antibiotics | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2007-02-13 | — | — | US | disclosed |