SCHEMBL14586643

SCHEMBL14586643

Cc1ccc(OCCc2ccccc2)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
L3MBTL1 Q9Y468 6/20 0.61
RAB9A P51151 4/20 0.61
ATM Q13315 2/20 0.61
HPGD P15428 5/20 0.57
NPC1 O15118 2/20 0.57
PPARG P37231 3/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MRGPRX4 Q96LA9 1/20 0.53
MAPK1 P28482 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877246 0.88 L3MBTL1 (0.50) MAPTL3MBTL1RAB9AATMHPGD
SCHEMBL130824 0.83 MRGPRX4 (0.68) MAPTL3MBTL1RAB9AATMHPGD
SCHEMBL19612232 0.82 NPC1 (0.53) RAB9AHPGDNPC1PPARGPPARD
SCHEMBL11360859 0.81 NPC1 (0.56) RAB9AHPGDNPC1PPARGSMN1; SMN2
SCHEMBL23271940 0.81 CNR1 (0.47) RAB9AMEN1KMT2A
SCHEMBL12260613 0.81 HPGD (0.49) HPGDPPARGPPARDPPARAHTR2C
SCHEMBL2989182 0.80 PPARG (0.61) PPARGMRGPRX4
Hydrochloric Acid SCHEMBL11354651 0.79 NPC1 (0.54) RAB9AHPGDNPC1SMN1; SMN2MRGPRX4
SCHEMBL26568933 0.79 MAPT (0.56) MAPTL3MBTL1RAB9AATMHPGD
SCHEMBL9705397 0.79 L3MBTL1 (0.51) MAPTL3MBTL1RAB9AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed