Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417459 | 0.89 | L3MBTL1 (0.60) | L3MBTL1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL19612460 | 0.85 | HTR1A (0.56) | L3MBTL1KCNH2PKMRAB9ACYP11B1 | |
| SCHEMBL17912813 | 0.85 | CYP11B1 (0.56) | DRD2MAPTRAB9ACYP11B1CYP11B2 | |
| SCHEMBL19612640 | 0.84 | HPGD (0.52) | KMT2ARAB9ACYP11B1CYP11B2MAPK14 | |
| Hydrochloric Acid SCHEMBL27883536 | 0.84 | L3MBTL1 (0.55) | L3MBTL1KCNH2HTTPKMMEN1 | |
| Hydrochloric Acid SCHEMBL27883534 | 0.84 | HTT (0.49) | L3MBTL1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL9808263 | 0.83 | L3MBTL1 (0.68) | L3MBTL1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL19612232 | 0.80 | NPC1 (0.53) | RAB9AHPGDNPC1 | |
| SCHEMBL28729767 | 0.80 | CYP11B1 (0.49) | DRD2RAB9ACYP11B1CYP11B2NPC1 | |
| SCHEMBL3047774 | 0.79 | HPGD (0.69) | L3MBTL1DRD2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159117-A | Reacting ketone or aldehyde with nitrites in presence of acid catalyst | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |