Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.75 |
| ▸ | DRD3 | P35462 | 13/20 | 0.71 |
| ▸ | DRD4 | P21917 | 12/20 | 0.71 |
| ▸ | HTR2A | P28223 | 9/20 | 0.71 |
| ▸ | DRD1 | P21728 | 8/20 | 0.71 |
| ▸ | DRD5 | P21918 | 7/20 | 0.71 |
| ▸ | MAOA | P21397 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | HTR2C | P28335 | 2/20 | 0.71 |
| ▸ | HTR2B | P41595 | 2/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.71 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MLNR | O43193 | 1/20 | 0.71 |
| ▸ | HTR3B | O95264 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609347 | 0.97 | DRD2 (0.76) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL30751117 | 0.97 | DRD2 (0.76) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL15486132 | 0.86 | DRD2 (0.76) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL29528854 | 0.86 | DRD2 (0.76) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL10571409 | 0.85 | DRD2 (0.94) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL14587008 | 0.84 | DRD2 (0.66) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL5608898 | 0.84 | DRD2 (0.69) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL30751116 | 0.84 | DRD2 (0.69) | DRD2DRD3DRD4HTR2ADRD1 | |
| Aripiprazole SCHEMBL29438823 | 0.83 | DRD2 (1.00) | DRD2DRD3DRD4HTR2ADRD1 | |
| Aripiprazole SCHEMBL982189 | 0.83 | DRD2 (1.00) | DRD2DRD3DRD4HTR2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125939-B2 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-9125939-B2 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | CHRNA6, GABBR1, CHRNA5 | DRD2 29/4885DRD3 82/4885DRD4 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.