Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6082094 | 0.89 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DHRH1IDO1 | |
| SCHEMBL7095750 | 0.89 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DHRH1IDO1 | |
| SCHEMBL6959819 | 0.89 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DHRH1IDO1 | |
| SCHEMBL5658840 | 0.75 | ADRA1A (0.42) | ADRA1AADRA1BADRA1DHRH1KDM1A | |
| SCHEMBL5662288 | 0.75 | ADRA1A (0.42) | ADRA1AADRA1BADRA1DHRH1KDM1A | |
| SCHEMBL8174001 | 0.75 | ADRA1A (0.42) | ADRA1AADRA1BADRA1DHRH1KDM1A | |
| SCHEMBL7075810 | 0.71 | ADRA1A (0.40) | ADRA1AADRA1BADRA1DHRH1IDO1 | |
| SCHEMBL7083169 | 0.71 | ADRA1A (0.40) | ADRA1AADRA1BADRA1DHRH1IDO1 | |
| SCHEMBL14587408 | 0.71 | HCAR3 (0.36) | ADRA1AADRA1BADRA1DHRH1HTR7 | |
| SCHEMBL7083166 | 0.71 | ADRA1A (0.40) | ADRA1AADRA1BADRA1DHRH1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | ADRA1A 46/4885ADRA1B 56/4885ADRA1D 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.