Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
| ▸ | GCGR | P47871 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | NME4 | O00746 | 1/20 | 0.40 |
| ▸ | GCDH | Q92947 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010743 | 0.99 | PPARG (0.44) | PPARGGCGRNR1H4SIRT5NME4 | |
| SCHEMBL5010499 | 0.92 | PPARG (0.45) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5010749 | 0.91 | PPARG (0.42) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL14587765 | 0.91 | PPARG (0.46) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5008260 | 0.90 | PPARG (0.41) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5008197 | 0.90 | PPARG (0.46) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5010546 | 0.89 | PPARG (0.48) | PPARGNR1H4 | |
| SCHEMBL5012114 | 0.88 | PPARG (0.45) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5010906 | 0.88 | NAMPT (0.43) | PPARGNR1H4HDAC4HDAC1HDAC7 | |
| SCHEMBL5012304 | 0.86 | PPARG (0.45) | PPARGNR1H4HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | PPARG 706/4885GCGR 37/4885NR1H4 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.