SCHEMBL14589302

SCHEMBL14589302

CCn1c2ccccc2c2cc(/C(C)=C3/OC(=S)N(CCc4ccc(OC)cc4)C3=O)ccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.42
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
RAB9A P51151 3/20 0.42
POLB P06746 3/20 0.42
MAPK1 P28482 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 8/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
SMPD1 P17405 3/20 0.41
LMNA P02545 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
HPGD P15428 3/20 0.41
HCRTR1 O43613 2/20 0.41
PAX8 Q06710 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14589301 0.85 MAPT (0.39) MAPTALDH1A1KDM4EHPGDHTT
SCHEMBL14589290 0.80 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL2622666 0.75 KDM4E (0.53) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL14589283 0.73 PTGER4 (0.45) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL23781994 0.71 MAPT (0.60) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL30000178 0.71 MAPT (0.60) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL14589362 0.70 KDM4E (0.43) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL17150143 0.68 SMPD1 (0.78) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29003693 0.67 MAPT (0.53) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL17242660 0.67 MAPT (0.66) MAPTALDH1A1MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169529-B2 Compound, photosensitive composition, lithographic printing plate precursor, and method of forming image FUJI PHOTO FILM CO., LTD. (JP) 2007-01-30 US disclosed
US-7169529-B2 Compound, photosensitive composition, lithographic printing plate precursor, and method of forming image FUJI PHOTO FILM CO., LTD. (JP) 2007-01-30 US disclosed