Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590721 | 0.92 | MAP2K1 (0.49) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL14590718 | 0.89 | MAP2K1 (0.46) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL14590729 | 0.89 | KMT2A (0.46) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL14590736 | 0.85 | KMT2A (0.43) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL6035697 | 0.82 | IDO1 (0.56) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL24849049 | 0.81 | MAP2K1 (0.56) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL5872850 | 0.81 | MAP2K1 (0.56) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL1340714 | 0.81 | MAP2K1 (0.64) | MAP2K1MAP2K2IDO1AURKATNFRSF1A | |
| SCHEMBL5989837 | 0.81 | IDO1 (0.47) | MAP2K1MAP2K2IDO1KMT2AMEN1 | |
| SCHEMBL4853895 | 0.80 | MEN1 (0.62) | MAP2K1MAP2K2IDO1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160915-B2 | N-methyl-substituted benzamidazoles | WARNER-LAMBERT COMPANY, LLC (US) | 2007-01-09 | — | — | US | disclosed |