Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492093 | 0.87 | CYP4Z1 (0.43) | TSHRMEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL14590803 | 0.83 | ABL1 (0.42) | TSHRMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL14590808 | 0.83 | SMN1; SMN2 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL14590809 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2ATDP1L3MBTL1ATM | |
| SCHEMBL14590805 | 0.75 | ABL1 (0.45) | TSHRTDP1L3MBTL1ATMALDH1A1 | |
| SCHEMBL3219477 | 0.74 | YWHAG (0.48) | NLRP3L3MBTL1ALDH1A1GAAGFER | |
| SCHEMBL3219080 | 0.71 | ABL1 (0.47) | TSHRMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11449778 | 0.70 | CYP1A2 (0.43) | TDP1PLA2G1BATG4BL3MBTL1THRA | |
| SCHEMBL20768627 | 0.70 | F2 (0.41) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20768626 | 0.70 | F2 (0.41) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166738-B2 | Non-nucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC (US) | 2007-01-23 | — | — | US | disclosed |