Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590802 | 0.89 | LMNA (0.44) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL3216630 | 0.86 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL14590805 | 0.83 | ABL1 (0.45) | LMNASMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL14590806 | 0.83 | GAA (0.44) | LMNASMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL14590803 | 0.80 | ABL1 (0.42) | LMNASMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL2561574 | 0.79 | GAA (0.66) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL25729047 | 0.79 | PPARG (0.51) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL11938336 | 0.76 | CYP4F2 (0.50) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL3213308 | 0.75 | DRD2 (0.49) | LMNASMN1; SMN2HTTPPARGPPARA | |
| SCHEMBL18310130 | 0.74 | KLKB1 (0.48) | LMNASMN1; SMN2HTTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166738-B2 | Non-nucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC (US) | 2007-01-23 | — | — | US | disclosed |