Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591399 | 0.84 | HTR6 (0.48) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL14591380 | 0.84 | NOTUM (0.52) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL14591384 | 0.81 | TMEM97 (0.47) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL14591400 | 0.81 | TMEM97 (0.55) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL17114834 | 0.80 | TMEM97 (0.79) | CXCR3SIGMAR1TMEM97 | |
| SCHEMBL14591391 | 0.78 | KDM4E (0.55) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL14591322 | 0.78 | PTGDR2 (0.58) | CXCR3HPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3157303 | 0.78 | HPGD (0.53) | CXCR3DRD3HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14571502 | 0.77 | CXCR3 (0.55) | CXCR3SIGMAR1HTR6DRD3TMEM97 | |
| SCHEMBL5690532 | 0.76 | TMEM97 (0.56) | CXCR3SIGMAR1TMEM97HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157463-B2 | Substituted piperidines/piperazines as melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157463-B2 | Substituted piperidines/piperazines as melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |