Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620282 | 1.00 | LMNA (0.37) | LMNAPOLBL3MBTL1TSHRCYP2D6 | |
| SCHEMBL5620287 | 1.00 | LMNA (0.37) | LMNAPOLBL3MBTL1TSHRCYP2D6 | |
| SCHEMBL3520901 | 0.79 | POLB (0.47) | LMNAPOLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL3519499 | 0.75 | POLB (0.50) | LMNAPOLBL3MBTL1TSHRKMT2A | |
| SCHEMBL10382409 | 0.73 | CYP2C19 (0.39) | LMNAPOLBL3MBTL1TSHRCYP2D6 | |
| SCHEMBL1441712 | 0.72 | PKM (0.41) | LMNATSHRCYP2D6CYP2C19KMT2A | |
| Acetic Acid SCHEMBL28604975 | 0.71 | LMNA (0.42) | LMNAPOLBL3MBTL1PKMKDM4E | |
| SCHEMBL30726842 | 0.71 | BRD4 (0.49) | LMNAPOLBL3MBTL1TSHRCYP2C19 | |
| SCHEMBL29216361 | 0.71 | LMNA (0.33) | LMNAPOLBL3MBTL1TSHRCYP2D6 | |
| SCHEMBL23811463 | 0.69 | CYP2D6 (0.39) | LMNATSHRCYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166754-B2 | Methods and compositions for enantioselective oxidation reactions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166754-B2 | Methods and compositions for enantioselective oxidation reactions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-01-23 | — | — | US | disclosed |