Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.80 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592252 | 0.93 | ITGB1 (0.69) | ITGB1ITGA4 | |
| SCHEMBL14592229 | 0.89 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL14592236 | 0.86 | ITGB1 (0.79) | ITGB1ITGA4 | |
| SCHEMBL14592272 | 0.85 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL12327278 | 0.84 | ITGA4 (0.87) | ITGB1ITGA4 | |
| SCHEMBL14592238 | 0.83 | ITGA4 (0.85) | ITGB1ITGA4 | |
| SCHEMBL14592251 | 0.83 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL14592191 | 0.82 | ITGB1 (0.86) | ITGB1ITGA4 | |
| SCHEMBL14592246 | 0.82 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL14592228 | 0.82 | ITGA4 (0.87) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |