Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459291 | 1.00 | LMNA (0.49) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL12903277 | 0.89 | LMNA (0.49) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL3142790 | 0.83 | LMNA (0.63) | LMNAAKT1TSHRPTPN1CDC25B | |
| SCHEMBL18227496 | 0.83 | LMNA (0.46) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL18227495 | 0.83 | LMNA (0.46) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL16464737 | 0.80 | LMNA (0.46) | LMNAMEN1KMT2ATSHRPTPN1 | |
| SCHEMBL27708134 | 0.80 | LMNA (0.43) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL27708155 | 0.80 | LMNA (0.43) | LMNAMEN1KMT2AAKT1TSHR | |
| SCHEMBL29606950 | 0.80 | MEN1 (0.68) | LMNAMEN1KMT2ATSHRPDE4D | |
| SCHEMBL334304 | 0.80 | MEN1 (0.68) | LMNAMEN1KMT2ATSHRPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718052-B2 | Catalysts and related processes for producing optically pure beta-lactones from aldehydes and compositions produced thereby | THE UNIVERSITY OF TOLEDO (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170021343-A1 | Catalysts and Related Processes For Producing Optically Pure Beta-Lactones From Aldehydes and Compositions Produced Thereby | THE UNIVERSITY OF TOLEDO (US) | 2017-01-26 | — | — | US | disclosed |
| US-9334266-B2 | Catalysts and related processes for producing optically pure beta-lactones from aldehydes and compositions produced thereby | THE UNIVERSITY OF TOLEDO (US) | 2016-05-10 | — | — | US | disclosed |
| US-20120196740-A1 | Process for Producing Optically Pure beta-Lactones from Aldehydes and Compositions Produced Thereby | UNIVERSITY OF TOLEDO (US) | 2012-08-02 | — | — | US | disclosed |
| EP-2473515-A1 | PROCESSES FOR PRODUCING OPTICALLY PURE -LACTONES FROM ALDEHYDES AND COMPOSITIONS PRODUCED THEREBY | UNIVERSITY OF TOLEDO (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011028309-A1 | PROCESSES FOR PRODUCING OPTICALLY PURE β-LACTONES FROM ALDEHYDES AND COMPOSITIONS PRODUCED THEREBY | UNIVERSITY OF TOLEDO (US) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170021343-A1 | Catalysts and Related Processes For Producing Optically Pure Beta-Lactones From Aldehydes and Compositions Produced Thereby | COASY, DCXR, TKT | LMNA 655/4885MEN1 898/4885KMT2A 1733/4885 |
| US-20120196740-A1 | Process for Producing Optically Pure beta-Lactones from Aldehydes and Compositions Produced Thereby | COASY, DCXR, DHPS | LMNA 828/4885MEN1 1101/4885KMT2A 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.