Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413890 | 1.00 | CACNA2D1 (0.45) | CACNA2D1CACNA1BCACNB1CACNA1CMC4R | |
| SCHEMBL5409320 | 0.86 | MC4R (0.47) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593354 | 0.85 | MC4R (0.66) | CACNA2D1CACNA1BCACNB1CACNA1CMC4R | |
| SCHEMBL5406356 | 0.85 | MC4R (0.66) | CACNA2D1CACNA1BCACNB1CACNA1CMC4R | |
| SCHEMBL5406440 | 0.85 | DPP4 (0.52) | CACNA2D1CACNA1BCACNB1MC4RCHRM2 | |
| SCHEMBL14593237 | 0.84 | ABCB1 (0.45) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593391 | 0.83 | CACNA2D1 (0.41) | CACNA2D1CACNA1BCACNB1CACNA1CMC4R | |
| SCHEMBL14593235 | 0.81 | GLS (0.49) | CHRM2CHRM4CHRM1CHRM3MAPT | |
| SCHEMBL7122471 | 0.81 | CHRM2 (0.47) | CACNA2D1CACNA1BCACNB1CACNA1CSOS1 | |
| SCHEMBL14593340 | 0.80 | CACNA2D1 (0.43) | CACNA2D1CACNA1BCACNB1CACNA1CSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |