Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406440 | 0.87 | DPP4 (0.52) | CHRM2CHRM4CHRM1CHRM3MC4R | |
| SCHEMBL5409320 | 0.86 | MC4R (0.47) | CHRM2CHRM4CHRM1CHRM3MC4R | |
| SCHEMBL14593448 | 0.84 | MC4R (0.65) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593236 | 0.84 | CACNA2D1 (0.45) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5413890 | 0.84 | CACNA2D1 (0.45) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593235 | 0.83 | GLS (0.49) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5424295 | 0.81 | CYP3A4 (0.51) | MC4RGPR119TP53 | |
| SCHEMBL5407838 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GPR119KDM4E | |
| SCHEMBL14593385 | 0.79 | MEN1 (0.46) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593345 | 0.79 | KDM4E (0.51) | ABCB1ALDH1A1GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |