Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 11/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593447 | 0.87 | MC4R (0.63) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5413611 | 0.87 | MC4R (0.63) | MC4R | |
| SCHEMBL5411133 | 0.87 | MC4R (0.63) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593354 | 0.85 | MC4R (0.66) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5406356 | 0.85 | MC4R (0.66) | MC4RCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14593418 | 0.84 | MC4R (0.60) | MC4RABCB1CHRM2CHRM4CHRM1 | |
| SCHEMBL14593237 | 0.84 | ABCB1 (0.45) | MC4RABCB1CHRM2CHRM4CHRM1 | |
| SCHEMBL14593313 | 0.82 | ALDH1A1 (0.49) | MC4R | |
| SCHEMBL14593267 | 0.81 | MC4R (0.64) | MC4R | |
| SCHEMBL14593321 | 0.81 | MC4R (0.55) | MC4RABCB1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |