SCHEMBL14596126

SCHEMBL14596126

C=Cc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.60
KMT2A Q03164 3/20 0.60
MAPT P10636 3/20 0.60
ALDH1A1 P00352 3/20 0.60
GAA P10253 2/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
HPGD P15428 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP3A4 P08684 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
PGR P06401 1/20 0.40
SLC6A2 P23975 1/20 0.40
PDE4A P27815 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547385 0.82 LMNA (0.69) LMNAKMT2AMAPTALDH1A1GAA
SCHEMBL6302167 0.81 LMNA (0.68) LMNAKMT2AMAPTALDH1A1GAA
SCHEMBL5324918 0.78 ALDH1A1 (0.68) LMNAKMT2AMAPTALDH1A1GAA
SCHEMBL12866514 0.76 LMNA (0.61) LMNAKMT2AMAPTALDH1A1GAA
SCHEMBL16312917 0.76 LMNA (0.65) LMNAKMT2AMAPTALDH1A1GAA
Sulisobenzone SCHEMBL29360128 0.75 LMNA (1.00) LMNAKMT2AMAPTALDH1A1GAA
Sulisobenzone SCHEMBL9474717 0.75 LMNA (1.00) LMNAKMT2AMAPTALDH1A1GAA
Sulisobenzone SCHEMBL16330 0.75 LMNA (1.00) LMNAKMT2AMAPTALDH1A1GAA
Sulisobenzone SCHEMBL167868 0.75 LMNA (1.00) LMNAKMT2AMAPTALDH1A1GAA
SCHEMBL10344888 0.74 LMNA (0.58) LMNAKMT2AMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1767353-A2 Lithographic printing plate precursor, lithographic printing method and cyanine dye FUJIFILM Corporation (JP) 2007-03-28 EP disclosed