Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.37 |
| ▸ | HTR2C | P28335 | 9/20 | 0.37 |
| ▸ | HTR2B | P41595 | 8/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450678 | 0.80 | ACHE (0.51) | HTR2AHTR1AALDH1A1ALOX15TSHR | |
| SCHEMBL409985 | 0.75 | ACHE (0.43) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL30298336 | 0.75 | ACHE (0.43) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL1953069 | 0.74 | ACHE (0.55) | ALDH1A1PSMB5KDM4E | |
| SCHEMBL24593559 | 0.73 | HTR2A (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL14625576 | 0.73 | HTR2C (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL24593640 | 0.73 | HTR2C (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL20203144 | 0.73 | HTR2C (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL3364642 | 0.73 | HTR2A (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 | |
| SCHEMBL24737425 | 0.73 | HTR2C (0.64) | HTR2AHTR2CHTR2BHTR1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | OGG1, CBR3, C1R | HTR2A 1173/4885HTR2C 987/4885HTR2B 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.