Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 6/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984420 | 0.82 | ESR2 (0.48) | ESR2HDAC4ALDH1A1CYP1A2MAPT | |
| SCHEMBL14596349 | 0.81 | PDGFRB (0.40) | ESR2NPC1RAB9AMAPTPDGFRB | |
| SCHEMBL13074637 | 0.77 | ESR2 (0.88) | ESR2NPC1RAB9AESR1CYP2C9 | |
| SCHEMBL10000243 | 0.72 | ESR2 (0.36) | ESR2HDAC4 | |
| SCHEMBL20924072 | 0.72 | NOTUM (0.50) | ESR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1713163 | 0.71 | HDAC4 (0.38) | ESR2USP7HDAC4ESR1CYP2C9 | |
| SCHEMBL17866598 | 0.70 | ESR2 (1.00) | ESR2ESR1CYP2C9 | |
| SCHEMBL2612209 | 0.70 | ESR2 (1.00) | ESR2ESR1CYP2C9 | |
| SCHEMBL11194904 | 0.69 | NPC1 (0.46) | NPC1RAB9AHDAC4ALDH1A1 | |
| SCHEMBL11190323 | 0.68 | ESR2 (0.41) | ESR2KMT2AHDAC4PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7195719-B1 | High polarization ferroelectric liquid crystal compositions | DISPLAYTECH, INC. (US) | 2007-03-27 | — | — | US | disclosed |