Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.57 |
| ▸ | NPY1R | P25929 | 9/20 | 0.57 |
| ▸ | NPY2R | P49146 | 7/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598311 | 1.00 | NPY4R (0.57) | NPY4RNPY5RNPY1RNPY2RMMP2 | |
| SCHEMBL14598296 | 0.94 | NPY4R (0.62) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL14598306 | 0.94 | NPY4R (0.62) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL5496626 | 0.89 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFOLH1 | |
| SCHEMBL5491137 | 0.89 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFOLH1 | |
| SCHEMBL5488639 | 0.88 | CHRNB2 (0.53) | NPY4RNPY5RNPY1RNPY2RFOLH1 | |
| SCHEMBL5487488 | 0.88 | CHRNB2 (0.53) | NPY4RNPY5RNPY1RNPY2RFOLH1 | |
| SCHEMBL14509120 | 0.88 | NPY4R (0.55) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL14509094 | 0.87 | NPY4R (0.60) | NPY4RNPY5RNPY1RNPY2RFOLH1 | |
| SCHEMBL14531792 | 0.87 | NPY4R (0.60) | NPY4RNPY5RNPY1RNPY2RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004644-A1 | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia | SIRCAR JAGADISH C | 2007-01-04 | — | — | US | disclosed |
| US-20070004644-A1 | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia | SIRCAR JAGADISH C | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004644-A1 | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia | CETP, LDLR, NPC1L1 | NPY4R 4005/4885NPY5R 4351/4885NPY1R 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.