Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | UBE2N | P61088 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599608 | 1.00 | FDPS (0.53) | FDPSNISCHPPARGPOLBKMT2A | |
| SCHEMBL14599619 | 1.00 | FDPS (0.53) | FDPSNISCHPPARGPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL8200421 | 0.92 | NAAA (0.55) | FDPSNISCHPPARGKMT2AALDH1A1 | |
| SCHEMBL14599609 | 0.86 | FDPS (0.51) | FDPSNISCHPPARGPOLBKMT2A | |
| SCHEMBL14599623 | 0.85 | SMN1; SMN2 (0.51) | FDPSNISCHPPARGPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL8197698 | 0.81 | FDPS (0.54) | FDPSNISCHPPARGPOLBKMT2A | |
| SCHEMBL25606151 | 0.81 | PPARG (0.74) | FDPSNISCHPPARGPOLBKMT2A | |
| SCHEMBL15329306 | 0.80 | FDPS (0.73) | FDPSNISCHPPARGPOLBKMT2A | |
| SCHEMBL7261735 | 0.80 | CD274 (0.64) | ALDH1A1 | |
| SCHEMBL15788315 | 0.77 | PPARG (0.61) | FDPSNISCHPPARGPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, GRN | FDPS 1572/4885NISCH 954/4885PPARG 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.